A general photocatalytic hydrodefluorination and defluoroalkylation of electronically-variable ArCF<sub>3</sub> by changing commercially-available arenethiolates
Yuanyang Jiang, Chenxiu Han, Zipeng Guo, Zhenyang Dai, Guangchao Liang, Shuo Guo, Nathaniel K. Szymczak, Pingping Tang
Abstract
The selection of electronically-different thiolate-based photosensitizers is employed to achieve a precise and specific C–F bond defluorination of a broad range of trifluoromethylarenes, enabling the synthesis of 88 α,α-difluoromethyl compounds.
Topics & Concepts
PhotocatalysisChemistryVariable (mathematics)PhotochemistryOrganic chemistryMathematicsCatalysisMathematical analysisFluorine in Organic ChemistryInorganic Fluorides and Related Compounds