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NeoFox: annotating neoantigen candidates with neoantigen features

Franziska Lang, Pablo Riesgo-Ferreiro, Martin Löwer, Uğur Şahin, Barbara Schrörs

2021Bioinformatics23 citationsDOIOpen Access PDF

Abstract

SUMMARY: The detection and prediction of true neoantigens is of great importance for the field of cancer immunotherapy. Wesearched the literature for proposed neoantigen features and integrated them into a toolbox called NEOantigen Feature toolbOX (NeoFox). NeoFox is an easy-to-use Python package that enables the annotation of neoantigen candidates with 16 neoantigen features. AVAILABILITY AND IMPLEMENTATION: NeoFox is freely available as an open source Python package released under the GNU General Public License (GPL) v3 license at https://github.com/TRON-Bioinformatics/neofox. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

Topics & Concepts

Python (programming language)MIT LicenseComputer scienceToolboxLicenseAnnotationOpen sourceProgramming languageComputational biologySoftwareArtificial intelligenceBiologyOperating systemvaccines and immunoinformatics approachesMonoclonal and Polyclonal Antibodies ResearchImmunotherapy and Immune Responses
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