New electrotriggers:<i>p</i>-methoxycarbonylbenzyl (pMCB) as an electroremovable protecting group for carboxylic acids, phosphoric acids and alcohols
Shulin Ning, Lianyou Zheng, Qiansong Gao, Lingling Shi, Yueling Liu, Chengcheng Sun, Zhuoqi Zhang, Jinbao Xiang
Abstract
A practical electrochemical method for the selective deprotection of the pMCB group was reported, which provides an efficient protocol for the controlled release of carboxylic acids, phosphoric acids and alcohols.
Topics & Concepts
Phosphoric acidChemistryElectrochemistryGroup (periodic table)Organic chemistryCarboxylic acidProtecting groupAlcoholCombinatorial chemistryAlkylPhysical chemistryElectrodeRadical Photochemical ReactionsChemical Synthesis and ReactionsChemical Synthesis and Analysis