Bovine colostrum: A source of bioactive compounds for prevention and treatment of gastrointestinal disorders
Rhaabe D.S. Gomes, Katya Anaya, Alyne B. S. Galdino, Juliana Paula Felipe de Oliveira, Marco Antônio Sundfeld da Gama, Caroline Addison Carvalho Xavier de Medeiros, Elaine C. Gavioli, Ana Lúcia Figueiredo Porto, Adriano Henrique do Nascimento Rangel
Abstract
Bovine colostrum is a rich source of nutrients and biologically active molecules known to be able to modulate the human immune system, such as lactoferrin, lysozyme, lactoperoxidase, immunoglobulins and growth factors. This comprehensive review aimed to gather evidence from animal experimentation and clinical trials that investigated the potential effects of bovine colostrum in preventing and treating diseases that affect the human gastrointestinal tract. Considered safe for human consumption, BC or its isolate components were used against a range of different gastrointestinal disorders. Beneficial effects were observed in several conditions: gastrointestinal infections, infectious diarrhoea, drug-induced lesions, gut-barrier malfunction, and inflammatory bowel disease. Under proper processing to maintain its components' integrity, BC products are valuable supplements with high nutraceutical value, capable of promoting and restoring gastrointestinal health.