Litcius/Paper detail

Switch to infliximab subcutaneous during SARS-CoV-2 pandemic: preliminary results

Federico Argüelles‐Arias, Paula Alvarez, Luisa Castro Laria, María Belén Maldonado Pérez, María Belvis Jiménez, Vicente Merino‐Bohórquez, Ángel Caunedo Álvarez, Miguel Ángel Calleja Hernández

2021Revista Española de Enfermedades Digestivas12 citationsDOIOpen Access PDF

Abstract

A new subcutaneous formulation of the infliximab biosimilar CT-P13 has recently been developed for the treatment of inflammatory bowel disease (IBD), providing response rates similar to intravenous treatment. The use of this new formulation was requested, in an effort to limit patient attendance at intravenous infusion centers and to maintain biological treatment during the COVID-19 pandemic. The objective of this observational, retrospective and descriptive study was to assess CT-P13 efficacy and safety after switching from intravenous to a subcutaneous formulation in patients with IBD receiving maintenance therapy. This article shows preliminary results after six months of follow-up.

Topics & Concepts

MedicineInfliximabBiosimilarPandemicCoronavirus disease 2019 (COVID-19)Observational studyDosingRetrospective cohort studyInflammatory bowel diseaseSubcutaneous injectionDiseaseIntensive care medicineInternal medicineInfectious disease (medical specialty)Biosimilars and Bioanalytical MethodsPharmaceutical studies and practicesHealth Systems, Economic Evaluations, Quality of Life