Translation of DNA Damage Response Inhibitors as Chemoradiation Sensitizers From the Laboratory to the Clinic
Leslie A. Parsels, Qiang Zhang, David Karnak, Joshua D. Parsels, Kwok Chi Lam, Henning Willers, Michael D. Green, Alnawaz Rehemtulla, Theodore S. Lawrence, Meredith A. Morgan
Topics & Concepts
In vivoRadiation therapyDNA damageImmunogenicityMedicineCancer researchRadiosensitizerPharmacologyComputational biologyBiologyDNAImmunologyInternal medicineBiotechnologyImmune systemGeneticsDNA Repair MechanismsPARP inhibition in cancer therapyCancer therapeutics and mechanisms