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Efficacy versus immunogenicity of LNP-mediated delivery of mRNA and self-amplifying RNA upon intravitreal injection in the mouse eye

Weiran Li, Helena Vanluchene, Laura Raes, Karen Peynshaert, Lien Veys, Sofía González Hernández, Emily De Lombaerde, Bruno G. De Geest, Niek N. Sanders, Lieve Moons, Koen Raemdonck, Lies De Groef, Katrien Remaut

2025Journal of Controlled Release14 citationsDOIOpen Access PDF

Topics & Concepts

ImmunogenicityMessenger RNARNAChemistryMedicinePharmacologyImmunologyImmune systemBiochemistryGeneRNA Interference and Gene DeliveryVirus-based gene therapy researchAdvanced biosensing and bioanalysis techniques
Efficacy versus immunogenicity of LNP-mediated delivery of mRNA and self-amplifying RNA upon intravitreal injection in the mouse eye | Litcius