Remodeling of structurally reinforced (TPU+PCL/PCL)-Hep electrospun small-diameter bilayer vascular grafts interposed in rat abdominal aortas
Zhiping Fang, Yuehao Xing, Han Wang, Xue Geng, Lin Ye, Aiying Zhang, Yongquan Gu, Zeng‐guo Feng
Abstract
cells were identified, but also a high content of elastin was evidenced due to the improvement of mechanical strength and compliance. These results indicated the feasibility and efficacy of inhibiting the aneurysm formation and boosting the vascular remodeling by incorporating TPU into PCL-Hep small-diameter artificial vascular grafts.
Topics & Concepts
BilayerChemistryBiophysicsAnatomyBiomedical engineeringMembraneMedicineBiologyBiochemistryElectrospun Nanofibers in Biomedical ApplicationsCardiac and Coronary Surgery TechniquesAortic aneurysm repair treatments