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Characterization of a commercially available line of iPSC hepatocytes as models of hepatocyte function and toxicity for regulatory purposes

Hisham Qosa, Alexandre J. S. Ribeiro, Neil R. Hartman, Donna A. Volpe

2021Journal of Pharmacological and Toxicological Methods18 citationsDOI

Topics & Concepts

ChemistryHepatocyteInduced pluripotent stem cellViability assayPharmacologyToxicantCerivastatinToxicityBiochemistryBiologyCellIn vitroEmbryonic stem cellGenePravastatinCholesterolOrganic chemistryPharmacogenetics and Drug MetabolismLiver physiology and pathologyDrug-Induced Hepatotoxicity and Protection
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