Typing of Neisseria gonorrhoeae Isolates in Shenzhen, China, from 2014 to 2018 Reveals the Shift of Genotypes Significantly Associated with Antimicrobial Resistance
Yizhun Li, Yamei Li, Leshan Xiu, Yaling Zeng, Chi Zhang, Li‐Ying Sun, LuLu Zhang, Feng Wang, Junping Peng
Abstract
The growing antimicrobial resistance (AMR) in Neisseria gonorrhoeae is a serious global threat to gonococcal therapy. Molecular typing is an ideal tool to reveal the association between specific genotypes and resistance phenotypes that provide effective data for tracking the transmission of resistant clones of N. gonorrhoeae . In our study, we aimed to describe the molecular epidemiology of AMR and the distribution of resistance-associated genotypes in Shenzhen, China, during 2014 to 2018.
Topics & Concepts
Neisseria gonorrhoeaeMultilocus sequence typingMolecular epidemiologyGenotypeTypingBiologyAntibiotic resistanceEpidemiologyDrug resistanceMicrobiologyGonorrheaGeneticsVirologyMedicineInternal medicineAntibioticsGeneHuman immunodeficiency virus (HIV)Reproductive tract infections researchBacterial Infections and VaccinesStreptococcal Infections and Treatments