Novel 18β-glycyrrhetinic acid derivatives as a Two-in-One agent with potent antimicrobial and anti-inflammatory activity
Borong Tu, Jinfeng Liang, Yi Ou, Xinyue Zhang, Wende Zheng, Rihui Wu, Li‐She Gan, Dongli Li, Yu‐Jing Lu, Jia‐Qiang Wu, W. David Hong, Kun Zhang, Panpan Wu, Jingwei Jin, Wing‐Leung Wong
Topics & Concepts
ChemistryAntimicrobialPharmacologyAnti-inflammatoryProinflammatory cytokineInflammationDownregulation and upregulationChemokinePI3K/AKT/mTOR pathwayTriterpeneIn vivoMechanism of actionBiochemistryIn vitroSignal transductionImmunologyBiologyMedicineReceptorGenePathologyBiotechnologyOrganic chemistryAlternative medicinePharmacological Effects of Natural CompoundsNatural product bioactivities and synthesisGinseng Biological Effects and Applications