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COVID-19 Induced Miller Fisher Syndrome Presenting With Autonomic Dysfunction: A Unique Case Report and Review of Literature

Subhrajyoti Biswas, Ritwik Ghosh, Arpan Mandal, Alak Pandit, Dipayan Roy, Samya Sengupta, Kaustav De, Bikash Chandra Swaika, Julián Benito‐León

2021The Neurohospitalist26 citationsDOIOpen Access PDF

Abstract

A plethora of neurological manifestations are associated with the 2019 coronavirus infectious disease (COVID-19). We hereby report the first case of a patient infected with SARS-CoV-2 who acutely presented with autonomic dysfunction preceding the onset of complete clinical picture of Miller Fisher syndrome. She was finally diagnosed to be a case of anti-ganglioside antibody positive post-COVID-19 Miller Fisher syndrome with dysautonomia and treated with intravenous immunoglobulin with an excellent response. We also discuss the plausible pathogenic mechanisms of COVID-19 induced Miller Fisher syndrome and furnish a review of the post-COVID-19 Miller Fisher syndrome cases reported.

Topics & Concepts

Miller-Fisher syndromeDysautonomiaCoronavirus disease 2019 (COVID-19)MedicineMillerSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)CoronavirusGuillain-Barre syndromeDiseasePediatricsInternal medicineInfectious disease (medical specialty)BiologyEcologyPeripheral Neuropathies and DisordersLong-Term Effects of COVID-19Autoimmune Neurological Disorders and Treatments
COVID-19 Induced Miller Fisher Syndrome Presenting With Autonomic Dysfunction: A Unique Case Report and Review of Literature | Litcius