Allosteric modulation and biased signalling at free fatty acid receptor 2
Xuan Zhang, Abdul-Akim D. Guseynov, Laura Jenkins, Alice Valentini, Sara Marsango, Katrine Schultz-Knudsen, Trond Ulven, Elisabeth Rexen Ulven, Irina G. Tikhonova, Graeme Milligan, Cheng Zhang
Topics & Concepts
G protein-coupled receptorAllosteric regulationTransmembrane domainTransmembrane proteinHelix (gastropod)IntracellularReceptorDrug discoveryMutagenesisG proteinSignal transductionCell biologyChemistryBiologyBiophysicsBiochemistryMutationGeneSnailEcologyReceptor Mechanisms and SignalingLipid Membrane Structure and BehaviorMass Spectrometry Techniques and Applications