Effect of Spermidine on Biofilm Formation in Escherichia coli K-12
Kullathida Thongbhubate, Yuko Nakafuji, Rina Matsuoka, Sonomi Kakegawa, Hideyuki Suzuki
Abstract
inhibits biofilm formation even though the spermidine is synthesized inside the cells from putrescine. Since PotD is significant for biofilm formation and there is no ortholog of the PotABCD transporter in humans, PotD could be a target for the development of biofilm inhibitors.
Topics & Concepts
SpermidineBiofilmPutrescineBiologyEscherichia coliBiochemistryCadaverineIntracellularMicrobiologyPolyamineBacteriaEnzymeGeneGeneticsPolyamine Metabolism and ApplicationsBacteriophages and microbial interactionsAmino Acid Enzymes and Metabolism