Obstructive sleep apnea-increased DEC1 regulates systemic inflammation and oxidative stress that promotes development of pulmonary arterial hypertension
Xiaoming Li, Xiang Zhang, Xiaozhi Hou, Xin Bing, Fangyuan Zhu, Xinhao Wu, Na Guo, Hui Zhao, Fenglei Xu, Ming Xia
Topics & Concepts
Oxidative stressHypoxia (environmental)Gene knockdownEndocrinologyInternal medicineInflammationTranscription factorMedicinePeroxisome proliferator-activated receptorReactive oxygen speciesMitochondrial ROSTumor necrosis factor alphaCancer researchChemistryImmunologyReceptorBiologyCell biologyApoptosisBiochemistryGeneOxygenOrganic chemistryPulmonary Hypertension Research and TreatmentsPeroxisome Proliferator-Activated ReceptorsCancer-related molecular mechanisms research