Bioengineering of bacteria for cancer immunotherapy
Dinh-Huy Nguyen, Ari Chong, Yeongjin Hong, Jung‐Joon Min
Abstract
Here, we provide a brief overview of the approaches and strategies underlying bacteria-based cancer immunotherapy (BCiT). We also describe and summarize research in the field of synthetic biology, which aims to regulate bacterial growth and gene expression for immunotherapeutic use. Finally, we discuss the current clinical status and limitations of BCiT.
Topics & Concepts
ImmunotherapyCancer immunotherapyComputational biologyCancerBacteriaBiologyGeneticsCancer Research and TreatmentsNanoplatforms for cancer theranosticsVirus-based gene therapy research