Frequent aneuploidy in primary human T cells after CRISPR–Cas9 cleavage
Alessio D. Nahmad, Eli Reuveni, Ella Goldschmidt, Tamar Tenne, Meytal Liberman, Miriam Horovitz‐Fried, Rami Khosravi, Hila Kobo, Eyal Reinstein, Asaf Madi, Uri Ben‐David, Adi Barzel
Topics & Concepts
CRISPRBiologyCas9T-cell receptorAneuploidyMolecular biologyTransfectionLocus (genetics)Guide RNAGenome editingGeneticsCell biologyGeneChromosomeT cellImmune systemCRISPR and Genetic EngineeringCAR-T cell therapy researchCytomegalovirus and herpesvirus research