Discovery and optimization of indirubin derivatives as novel ferroptosis inducers for the treatment of colon cancer
Jiangmin Zhu, Chen Chen, Min Kong, Ling Zhu, Yalin Li, Jianfei Zhang, Zhanpeng Yu, Shi-shu Xu, Ling‐Yi Kong, Jian‐Guang Luo, Jian‐Guang Luo
Topics & Concepts
GPX4ChemistryInducerIn vivoAntioxidantCytotoxicityGlutathioneCancer cellCancer researchEnzymeColorectal cancerCancerBiochemistryPharmacologyGlutathione peroxidaseIn vitroBiologyGeneGeneticsBiotechnologyFerroptosis and cancer prognosisCancer Mechanisms and TherapyPeptidase Inhibition and Analysis