RBBP4 regulates the expression of the Mre11-Rad50-NBS1 (MRN) complex and promotes DNA double-strand break repair to mediate glioblastoma chemoradiotherapy resistance
Junjie Li, Chong Song, Junwei Gu, Chiyang Li, Wenrui Zang, Linyong Shi, Lei Chen, Liwen Zhu, Min Zhou, Tong Wang, Hong Li, Songtao Qi, Yuntao Lu
Topics & Concepts
Rad50DNA repairTemozolomideDNA damageCancer researchRadioresistanceBiologyRadiation therapyRAD51DNAGliomaTranscription factorMedicineDNA-binding proteinGeneticsCell cultureGeneInternal medicineDNA Repair MechanismsGlioma Diagnosis and TreatmentCancer Genomics and Diagnostics