Synthesis and mechanistic investigations of pH-responsive cationic poly(aminoester)s
Timothy R. Blake, Wilson C. Ho, Christopher R. Turlington, Xiaoyu Zang, Melanie A. Huttner, Paul A. Wender, Robert M. Waymouth
Abstract
-hydroxyethyl substituents are readily cleaved (by intramolecular attack) or hydrolyzed, representing dynamic "dual function" materials that are initially polycationic and transform with changing environment to neutral products.
Topics & Concepts
Cationic polymerizationChemistryPolymer chemistrybiodegradable polymer synthesis and propertiesSynthesis and properties of polymersAntimicrobial agents and applications