Long-term cerebrovascular dysfunction in the offspring from maternal electronic cigarette use during pregnancy
Emily N. Burrage, Eiman Aboaziza, Lance Hare, Sarah Reppert, Josh Moore, William T. Goldsmith, Eric E. Kelley, Amber Mills, Duaa Dakhlallah, Paul D. Chantler, I. Mark Olfert
Abstract
These data established that vaping electronic cigarettes during pregnancy, with or without nicotine, is not safe and confers significant risk potential to the cerebrovascular health of offspring in early and adult life. A key finding is that vaping without nicotine does not protect offspring from cerebrovascular dysfunction and results in the same level of cerebrovascular dysfunction (compared with maternal vaping with nicotine), indicating that the physical and/or chemical properties from the base solution (other than nicotine) are responsible for the cerebrovascular dysfunction that we observed. Listen to this article's corresponding podcast at https://ajpheart.podbean.com/e/maternal-vaping-impairs-vascular-function-in-theoffspring/.