Stereoselective α-Chlorination of β-Keto Esters in the Presence of Hybrid Amide-Based <i>Cinchona</i> Alkaloids as Catalysts
Maciej Majdecki, Piotr Grodek, Janusz Jurczak
Abstract
core allows the chlorination reaction to be conducted in a highly enantioselective manner with various indanone and tetralone carboxylate esters.
Topics & Concepts
ChemistryCinchonaEnantioselective synthesisTetraloneAmideCatalysisCinchona AlkaloidsOrganic chemistryOrganocatalysisStereoselectivityAsymmetric inductionCinchonidineAsymmetric Synthesis and CatalysisFluorine in Organic ChemistryAdvanced Synthetic Organic Chemistry