Yeast powder derived carbon quantum dots for dopamine detection and living cell imaging
Xue Cao, Congying Shao, Cheng Zhang, Mengna Liang, Yongxiang Wang, Jun Cheng, Shun Lu
Abstract
a simple hydrothermal approach of using yeast powder and regarded as the fluorescent nanoprobe to directly monitor the DA concentration. The as-prepared detection platform exhibited excellent sensitivity and selectivity toward DA with a low detection limit of 30 nM and a wide linear range of 0.05-150 μM. Benefiting from these outstanding features, the developed label-free method has been successfully applied for fast DA detection in human serum samples with satisfactory recoveries. Furthermore, it demonstrated that the Y-CDs were well suitable for live cell imaging and showed low toxicity toward MCF-7 cells. Consequently, this work will facilitate the great potential of the versatile Y-CDs in developing biosensors for clinical diagnosis and other biological applications.