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Tracking R of COVID-19: A new real-time estimation using the Kalman filter

Francisco Arroyo-Marioli, Francisco Bullano, Simas Kučinskas, Carlos Rondón-Moreno

2021PLoS ONE227 citationsDOIOpen Access PDF

Abstract

We develop a new method for estimating the effective reproduction number of an infectious disease ( <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline" id="M3"> <mml:mi mathvariant="script">R</mml:mi> </mml:math> ) and apply it to track the dynamics of COVID-19. The method is based on the fact that in the SIR model, <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline" id="M4"> <mml:mi mathvariant="script">R</mml:mi> </mml:math> is linearly related to the growth rate of the number of infected individuals. This time-varying growth rate is estimated using the Kalman filter from data on new cases. The method is easy to implement in standard statistical software, and it performs well even when the number of infected individuals is imperfectly measured, or the infection does not follow the SIR model. Our estimates of <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline" id="M5"> <mml:mi mathvariant="script">R</mml:mi> </mml:math> for COVID-19 for 124 countries across the world are provided in an interactive online dashboard , and they are used to assess the effectiveness of non-pharmaceutical interventions in a sample of 14 European countries.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)AlgorithmComputer scienceKalman filter2019-20 coronavirus outbreakStatisticsArtificial intelligenceMathematicsInfectious disease (medical specialty)BiologyMedicineVirologyDiseaseOutbreakPathologyCOVID-19 epidemiological studiesSARS-CoV-2 and COVID-19 ResearchInfluenza Virus Research Studies
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