Functional interrogation of DNA damage response variants with base editing screens
Raquel Cuella-Martin, Samuel B. Hayward, Xiao Fan, Xiao Chen, Jen‐Wei Huang, Angelo Taglialatela, Giuseppe Leuzzi, Junfei Zhao, Raúl Rabadán, Chao Lü, Yufeng Shen, Alberto Ciccia
Topics & Concepts
BiologyDNA damageGeneticsGeneGenome editingLoss functionCRISPRDNA repairMutationPhenotypeDeubiquitinating enzymeGenetic screenDNAComputational biologyUbiquitinCRISPR and Genetic EngineeringCytomegalovirus and herpesvirus researchDNA Repair Mechanisms