Silica nanoparticle design for colorectal cancer treatment: Recent progress and clinical potential
Jin Meng, Zhi-Gang Wang, Xin Zhao, Ying Wang, De-Yu Chen, De-Long Liu, Cheng-Chun Ji, Tian-Fu Wang, Li-Mei Zhang, Hai-Xia Bai, Bo-Yang Li, Yuan Liu, Lei Wang, Wei-Gang Yu, Zhi-Tao Yin
Abstract
Colorectal cancer (CRC) is the third most common cancer worldwide and the second most common cause of cancer death. Nanotherapies are able to selectively target the delivery of cancer therapeutics, thus improving overall antitumor efficiency and reducing conventional chemotherapy side effects. Mesoporous silica nanoparticles (MSNs) have attracted the attention of many researchers due to their remarkable advantages and biosafety. We offer insights into the recent advances of MSNs in CRC treatment and their potential clinical application value.
Topics & Concepts
MedicineColorectal cancerMesoporous silicaCancerBiosafetyCancer treatmentNanotechnologyCancer researchInternal medicinePathologyMesoporous materialMaterials scienceCatalysisChemistryBiochemistryNanoparticle-Based Drug DeliveryNanoplatforms for cancer theranosticsMesoporous Materials and Catalysis