Pharmaceutical perspectives of thiazole analogues: An overview
Archana R. Patil, Basappa C. Yallur, Sampath Chinnam, Guddekoppa S. Ananthnag, C. R. Santhosh, Geetika Pant, Sanjan Kumar, Manjuanth D. Hadagali
Abstract
Thiazole derivatives have attracted considerable attention in medicinal chemistry due to their promising biological activities. This review article provides a comprehensive overview on the pharmaceutical applications of the thiazole derivatives, exploring their structural activity relationship and medical applications. We discuss the anti-cancer, anti-inflammatory, anti- oxidant, BSA and DNA interaction properties of thiazole derivatives highlighting their role in drug development. This review will be a valuable resource in medicinal chemistry. This could lead to development of drugs containing thiazoles and improve bio-compatibility and efficiency of derivatives.