Temperature and light dual-responsive hydrogels for anti-inflammation and wound repair monitoring
Ji Jiang, Yuan Tian, Xiaoyang Wu, Mingze Zeng, Chengheng Wu, Dan Wei, Hongrong Luo, Jing Sun, Jie Ding, Hongsong Fan
Abstract
'-dinitroso-1,4-phenylenediamine (BNN6). When exposed to near-infrared (NIR) laser irradiation, these PDA@BNN6 nanoparticles release NO to provide potent antibacterial and anti-inflammatory effects. The integration of continuous wireless temperature monitoring with NO release within a single hydrogel dressing represents a significant advancement in clinical wound care. This dual-functional platform not only provides real-time diagnostic capabilities but also offers therapeutic interventions to manage wound infections and promote tissue regeneration. Our research highlights the potential of PHDNN6 to revolutionize wound management by offering a comprehensive solution that addresses both the diagnostic and therapeutic needs in wound healing.