Circulating cell-free mtDNA release is associated with the activation of cGAS-STING pathway and inflammation in mitochondrial diseases
Xutong Zhao, Meng Yu, Yawen Zhao, Yiming Zheng, Lingchao Meng, Kang Du, Zhiying Xie, He Lv, Wei Zhang, Jing Liu, Qingqing Wang, Yun Yuan, Zhaoxia Wang, Jianwen Deng
Topics & Concepts
InflammationMitochondrial DNAMitochondrionNeurologyStingMedicineImmunologyBiologyNeuroscienceCell biologyGeneticsGeneEngineeringAerospace engineeringinterferon and immune responsesInflammasome and immune disordersMitochondrial Function and Pathology