Litcius/Paper detail

Advances in biomarkers and techniques for pancreatic cancer diagnosis

Haotian Wu, Suwen Ou, Hongli Zhang, Rui Huang, Shan Yu, Ming Zhao, Sheng Tai

2022Cancer Cell International58 citationsDOIOpen Access PDF

Abstract

Pancreatic cancer is the most lethal type of malignancy and is characterized by high invasiveness without severe symptoms. It is difficult to detect PC at an early stage because of the low diagnostic accuracy of existing routine methods, such as abdominal ultrasound, CT, MRI, and endoscopic ultrasound (EUS). Therefore, it is of value to develop new diagnostic techniques for early detection with high accuracy. In this review, we aim to highlight research progress on novel biomarkers, artificial intelligence, and nanomaterial applications on the diagnostic accuracy of pancreatic cancer.

Topics & Concepts

Pancreatic cancerMedicineMalignancyEndoscopic ultrasoundRadiologyStage (stratigraphy)CancerDiagnostic accuracyAbdominal ultrasoundPathologyInternal medicinePaleontologyBiologyExtracellular vesicles in diseaseMicroRNA in disease regulationPancreatic and Hepatic Oncology Research