Yi-qi-hua-yu-jie-du decoction induces ferroptosis in cisplatin-resistant gastric cancer via the AKT/GSK3β/NRF2/GPX4 axis
Wenjie Huang, Fang Wen, Peipei Yang, Li Ye, Qiurong Li, Peng Shu
Topics & Concepts
CisplatinGlutathioneProtein kinase BReactive oxygen speciesChemistryGPX4ApoptosisPI3K/AKT/mTOR pathwayPharmacologyCancer researchCancer cellCancerBiochemistryMedicineChemotherapyInternal medicineEnzymeGlutathione peroxidaseFerroptosis and cancer prognosisImmune cells in cancerCancer-related molecular mechanisms research