Cleavage of viral DNA by restriction endonucleases stimulates the type II CRISPR-Cas immune response
Pascal Maguin, Andrew Varble, Joshua W. Modell, Luciano A. Marraffini
Topics & Concepts
CRISPRBiologyRestriction enzymeDNAEndonucleaseGeneticsGenomeCas9Immune systemInnate immune systemAcquired immune systemTrans-activating crRNACleaveComputational biologyGeneCRISPR and Genetic EngineeringCytomegalovirus and herpesvirus researchHIV Research and Treatment