COF-based nanoreactors for click-activated prodrug delivery and precise anti-vascular therapy
Peng Wang, Mili Li, Fang Zhou, Yue Yang, Xia Yin, Xiaobing Zhang, Guosheng Song
Abstract
Nanoconfined biorthogonal reaction in defined COF cages boosts the click efficiency of prodrug activation and enhances anti-vascular therapy.
Topics & Concepts
Bioorthogonal chemistryNanoreactorProdrugClick chemistryCovalent bondTetrazineChemistryCombinatorial chemistryAptamerNanotechnologyMaterials scienceNanoparticleOrganic chemistryBiochemistryGeneticsBiologyNanoplatforms for cancer theranosticsClick Chemistry and ApplicationsRadiopharmaceutical Chemistry and Applications