Litcius/Paper detail

Functionality of garlic sulfur compounds (Review)

Taiichiro Seki, Takashi Hosono

2025Biomedical Reports9 citationsDOIOpen Access PDF

Abstract

Garlic (<em>Allium sativum</em> L.), a perennial herbaceous edible plant, is classified in the Amaryllidaceae family and belongs to the Allium genus. It has a higher sulfur content than other plants. Garlic is extensively used worldwide as a spice and flavoring agent, and it generates a unique aroma during cooking. Garlic possesses various properties, including anti‑thrombotic, antioxidant, blood cholesterol‑lowering, anti‑obesity and anti‑dementia effects. These properties have been attributed to various garlic‑derived sulfur‑containing compounds, including <em>S</em>‑allyl cysteine, allicin, allyl sulfides and ajoene. The present review provides an overview of the mechanisms that underlie the generation of odor compounds in garlic and discusses certain observed effects of garlic consumption.

Topics & Concepts

Molecular medicineCell cycleOncogeneSulfurCancerComputational biologyBiologyChemistryGeneticsOrganic chemistryGarlic and Onion StudiesSelenium in Biological SystemsAgriculture and Biological Studies