Natural bioactive compounds from marine fungi (2017–2020)
Huan‐Nan Wang, Shanshan Sun, Mengzhen Liu, Maocai Yan, Yufeng Liu, Zheng Zhu, Zhen Zhang
Abstract
Secondary metabolites generated by marine fungi have relatively small molecular weights and excellent activities and have become an important source for developing drug lead compounds. The review summarizes the structures of novel small-molecule compounds derived from marine fungi in recent years; introduces representative monomers in antimicrobial, antitumor, anti-viral, and anti-neuritis aspects; and discusses their biological activities and molecular mechanisms. This review will act as a guide for further discovering marine-derived drugs with novel chemical structures and specific targeting mechanisms.
Topics & Concepts
AntimicrobialMarine fungiDrug discoveryChemistryDrugComputational biologyBiologyBiochemistryPharmacologyOrganic chemistryBotanyMicrobial Natural Products and BiosynthesisMarine Sponges and Natural ProductsBioactive Compounds and Antitumor Agents