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Improved functional mapping of complex trait heritability with GSA-MiXeR implicates biologically specific gene sets

Oleksandr Frei, Guy Hindley, Alexey Shadrin, Dennis van der Meer, Bayram Cevdet Akdeniz, Espen Hagen, Weiqiu Cheng, Kevin S. O’Connell, Shahram Bahrami, Nadine Parker, Olav B. Smeland, Dominic Holland, Christiaan de Leeuw, Daniëlle Posthuma, Ole A. Andreassen, Anders M. Dale

2024Nature Genetics31 citationsDOIOpen Access PDF

Topics & Concepts

BiologyLinkage disequilibriumHeritabilityComputational biologyGeneticsGeneQuantitative trait locusGenome-wide association studyGenetic associationTraitGene regulatory networkAlleleSingle-nucleotide polymorphismHaplotypeGene expressionGenotypeComputer scienceProgramming languageGenetic Associations and EpidemiologyBioinformatics and Genomic NetworksGenetic Mapping and Diversity in Plants and Animals
Improved functional mapping of complex trait heritability with GSA-MiXeR implicates biologically specific gene sets | Litcius