Mechanistic and thermodynamic characterization of antiviral inhibitors targeting nucleocapsid N-terminal domain of SARS-CoV-2
Preeti Dhaka, Ankur Singh, Shweta Choudhary, Rama Krishna Peddinti, Pravindra Kumar, Gaurav Kumar Sharma, Shailly Tomar
Topics & Concepts
Isothermal titration calorimetrySmall moleculeRNAChemistryBinding siteVirologyCoronavirusPlasma protein bindingBiochemistryBiologyComputational biologyCoronavirus disease 2019 (COVID-19)MedicineGeneInfectious disease (medical specialty)DiseasePathologyViral gastroenteritis research and epidemiologySARS-CoV-2 and COVID-19 ResearchViral Infections and Immunology Research