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Identification of second primary tumors from lung metastases in patients with esophageal squamous cell carcinoma using whole-exome sequencing

Liyan Xue, Lin Li, Xinyi Fan, Zitong Zhao, Wei Zhou, Zhimin Feng, Linxiu Liu, Lin Hua, Lin Li, Xuemin Xue, Xuanlin Huang, Peide Huang, Jia Guo, Peina Du, Ning Lü, Lin Li, Qi-Min Zhan, Yongmei Song

2020Theranostics12 citationsDOIOpen Access PDF

Abstract

Our data demonstrate the limitations and insufficiency of clinicopathological criteria and that WES could be useful in understanding the clonal relationships of multiple SCCs.

Topics & Concepts

Exome sequencingMedicineEsophageal squamous cell carcinomaIdentification (biology)PathologyBasal cellLungCarcinomaOncologySquamous-cell carcinoma of the lungExomeCancer researchInternal medicineBiologyMutationGeneGeneticsBotanyCancer Genomics and DiagnosticsLung Cancer Treatments and MutationsMedical Imaging and Pathology Studies
Identification of second primary tumors from lung metastases in patients with esophageal squamous cell carcinoma using whole-exome sequencing | Litcius