Associations of Circulating Estrogens and Estrogen Metabolites with Fecal and Oral Microbiome in Postmenopausal Women in the Ghana Breast Health Study
Zeni Wu, Ruth M. Pfeiffer, Doratha A. Byrd, Yunhu Wan, Daniel Ansong, Joe‐Nat Clegg‐Lamptey, Beatrice Wiafe‐Addai, Lawrence Edusei, Ernest Adjei, Nicholas Titiloye, Florence Dedey, Francis Aitpillah, Joseph K. Oppong, Verna Vanderpuye, Ernest Osei‐Bonsu, Casey Dagnall, Kristine Jones, Amy Hutchinson, Belynda Hicks, Thomas U. Ahearn, Rob Knight, Richard Biritwum, Joel Yarney, Seth Wiafe, Baffour Awuah, Kofi Nyarko, Montserrat García‐Closas, Rashmi Sinha, Jonine D. Figueroa, Louise A. Brinton, Britton Trabert, Emily Vogtmann
Abstract
Several epidemiologic studies have found associations of urinary estrogens and estrogen metabolites with the fecal microbiome. However, urinary estrogen concentrations are not strongly correlated with serum estrogens, a known risk factor for breast cancer.