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N6-adenomethylation of GsdmC is essential for Lgr5+ stem cell survival to maintain normal colonic epithelial morphogenesis

Jie Du, Rajesh Sarkar, Yan Li, Lei He, Wenjun Kang, Wang Liao, Weicheng Liu, Tivoli Nguyen, Linda Zhang, Zifeng Deng, Urszula Dougherty, Sonia S. Kupfer, Mengjie Chen, Joel Pekow, Marc Bissonnette, Chuan He, Yan Chun Li, Yan Chun Li, Yan Chun Li

2022Developmental Cell40 citationsDOIOpen Access PDF

Topics & Concepts

LGR5BiologyCell biologyStem cellOrganoidMorphogenesisApoptosisProgrammed cell deathIntestinal epitheliumEpitheliumCancer stem cellBiochemistryGeneticsGeneEpigenetics and DNA MethylationRNA modifications and cancerCongenital Diaphragmatic Hernia Studies
N6-adenomethylation of GsdmC is essential for Lgr5+ stem cell survival to maintain normal colonic epithelial morphogenesis | Litcius