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Umbrella Sampling-Based Method to Compute Ligand-Binding Affinity

Sơn Tùng Ngô, Minh Quan Pham

2021Methods in molecular biology23 citationsDOI

Topics & Concepts

Umbrella samplingPotential of mean forceHistogramSampling (signal processing)Ligand (biochemistry)HarmonicChemistryBinding siteMolecular dynamicsComputational chemistryComputer sciencePhysicsBiochemistryArtificial intelligenceOpticsQuantum mechanicsReceptorImage (mathematics)DetectorProtein Structure and DynamicsEnzyme Structure and FunctionRNA and protein synthesis mechanisms
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