Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer
Priscilla Cheung, Jordi Xiol, Michael T. Dill, Wei-Chien Yuan, Riccardo Panero, Jatin Roper, Fernando G. Osorio, Dejan Maglic, Qi Li, Basanta Gurung, Raffaele Calogero, Ömer Yılmaz, Junhao Mao, Fernando D. Camargo
Topics & Concepts
BiologyLGR5Wnt signaling pathwayHippo signaling pathwayCancer researchColorectal cancerReprogrammingStem cellCell biologyKinaseTranscription factorMouse model of colorectal and intestinal cancerCancer stem cellCancerSignal transductionCellGeneticsGeneHippo pathway signaling and YAP/TAZWnt/β-catenin signaling in development and cancer