<i>In situ</i> self-assembly of conjugated polyelectrolytes for cancer targeted imaging and photodynamic therapy
Syeda Sadia Khatoon, Yanyan Chen, Hao Zhao, Fengting Lv, Libing Liu, Shu Wang
Abstract
). Due to this unique self-aggregation property, PFT-SH was successfully used to achieve in situ self-assembly specifically inside cancer cells for targeted imaging. Both the specific aggregation of PFT-SH in cancer cells and its ROS producing ability led to its use in the targeted killing of cancer cells through efficient photodynamic therapy.
Topics & Concepts
Photodynamic therapyIn situConjugated systemCancer therapyCancerCancer imagingNanotechnologyChemistryBiophysicsMedicineMaterials scienceBiologyInternal medicineOrganic chemistryPolymerNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsAdvanced biosensing and bioanalysis techniques