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Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1

Wen-Lin Su, Chih-Pei Lin, Hui-Ching Hang, Ping-Sheng Wu, Ching‐Feng Cheng, You‐Chen Chao

2020Journal of Microbiology Immunology and Infection38 citationsDOIOpen Access PDF

Abstract

Increased heme levels, anemia, and desaturation occur during infection. We aimed to compare the levels of heme, heme oxygenase-1 (HO-1), ferritin, and bilirubin in coronavirus disease 2019 (COVID-19) patients at different saturation levels. Heme and HO-1 enzyme levels significantly increased in the low SpO2 group, but further studies are required.

Topics & Concepts

HemeHeme oxygenaseBilirubinFerritinCoronavirus disease 2019 (COVID-19)MedicineChemistryInternal medicineEnzymeDiseaseBiochemistryInfectious disease (medical specialty)Heme Oxygenase-1 and Carbon MonoxideThermal Regulation in MedicineCOVID-19 Clinical Research Studies
Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1 | Litcius