Early-life fecal microbiome and metabolome dynamics in response to an intervention with infant formula containing specific prebiotics and postbiotics
Alfonso Rodríguez‐Herrera, Sebastian Tims, J. Polman, Rocío Porcel Rubio, Antonio Muñoz Hoyos, Massimo Agosti, Gianluca Lista, Luigi Corvaglia, Jan Knol, Guus Roeselers, Juan L. Pérez Navero
2022American Journal of Physiology-Gastrointestinal and Liver Physiology24 citationsDOIOpen Access PDF
Abstract
Untargeted metabolomics techniques can provide a "snapshot" of an ecosystem in response to environmental stimuli, such as nutritional interventions. Our analyses of fecal samples from infants demonstrate the potential of phenotyping by metabolomics while deciphering the complex interactions of early-life nutrition and gut microbiome development.
Topics & Concepts
MetabolomeFecesGut floraMicrobiomeMetaboliteMetabolomicsPhysiologyBiologyInfant formulaBifidobacteriumMedicineLactobacillusFood scienceBioinformaticsMicrobiologyEndocrinologyImmunologyFermentationGut microbiota and healthDiet and metabolism studiesProbiotics and Fermented Foods