Prion-like C-Terminal Domain of TDP-43 and α-Synuclein Interact Synergistically to Generate Neurotoxic Hybrid Fibrils
Shailendra Dhakal, Courtney E. Wyant, Hannah E. George, Sarah E. Morgan, Vijayaraghavan Rangachari
Topics & Concepts
FibrilProtein aggregationChemistryDementia with Lewy bodiesStress granuleBiophysicsCell biologyMonomerAmyloid (mycology)Alpha-synucleinBiochemistryParkinson's diseaseBiologyDementiaDiseaseMedicineTranslation (biology)GenePathologyMessenger RNAInorganic chemistryOrganic chemistryPolymerAmyotrophic Lateral Sclerosis ResearchPrion Diseases and Protein MisfoldingAlzheimer's disease research and treatments