Efficacy and safety of maralixibat treatment in patients with Alagille syndrome and cholestatic pruritus (ICONIC): a randomised phase 2 study
Emmanuel Gonzalès, Winita Hardikar, Michael Stormon, Alastair Baker, Loreto Hierro, Dorota Gliwicz, Florence Lacaille, Alain Lachaux, Ekkehard Sturm, Kenneth D.R. Setchell, Ciara Kennedy, Alejandro Dorenbaum, Jana I. Steinmetz, Nirav K. Desai, Andrew J Wardle, Will Garner, Pamela Vig, Thomas Jaecklin, Étienne Sokal, Emmanuel Jacquemin
Topics & Concepts
Alagille syndromeMedicinePlaceboCholestasisClinical endpointPopulationInternal medicineGastroenterologyAdverse effectBile acidRandomized controlled trialPediatricsPathologyEnvironmental healthAlternative medicinePediatric Hepatobiliary Diseases and TreatmentsDrug Transport and Resistance MechanismsGallbladder and Bile Duct Disorders