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DNA polymerase theta (Polθ) – an error-prone polymerase necessary for genome stability

Alessandra Brambati, Raymond Mario Barry, Agnel Sfeir

2020Current Opinion in Genetics & Development114 citationsDOIOpen Access PDF

Topics & Concepts

BiologyDNA polymeraseHomologous recombinationPolymeraseDNA repairNon-homologous end joiningGeneticsGenome instabilityGenomeMolecular biologyDNA polymerase betaDNADNA damageCancer researchGeneBase excision repairDNA Repair MechanismsCarcinogens and Genotoxicity AssessmentCancer therapeutics and mechanisms
DNA polymerase theta (Polθ) – an error-prone polymerase necessary for genome stability | Litcius