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Innovations and Inventions: Why Was the Ugi Reaction Discovered Only 37 Years after the Passerini Reaction?

Alexander Dömlingꝉ

2022The Journal of Organic Chemistry31 citationsDOIOpen Access PDF

Abstract

= 4)]. In this work, a historical but contemporary perspective of the discoveries and innovations of the two reactions is given. From a bird's eye view and in a more general sense, the discovery of novel reactions is discussed and how it relates to inventions and innovations.

Topics & Concepts

Ugi reactionPerspective (graphical)Component (thermodynamics)Space (punctuation)Computer scienceCombinatorial chemistryChemistryOrganic chemistryArtificial intelligencePhysicsIsocyanideThermodynamicsOperating systemMulticomponent Synthesis of HeterocyclesChemical Synthesis and AnalysisClick Chemistry and Applications