Direct C(sp<sup>3</sup>)–H functionalization with aryl and alkyl radicals as intermolecular hydrogen atom transfer (HAT) agents
Jia‐Lin Tu, Binbin Huang
Abstract
generated aryl/alkyl radicals and categorizes the procedures by the specific radical precursors applied. With an emphasis on the reaction conditions, mechanisms and representative substrate scopes of these protocols, this review aims to demonstrate the current trends and future challenges of this emerging field.
Topics & Concepts
Intermolecular forceSurface modificationArylHydrogen atomAlkylChemistryRadicalAtom (system on chip)Hydrogen bondPhotochemistryMedicinal chemistryOrganic chemistryMoleculePhysical chemistryComputer scienceEmbedded systemRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques